The essays in this issue indicate that in reflecting on the use of artificial intelligence (AI) in medicine, society should go beyond the technical level. While it is important to determine both the benefits and the risks of AI systems for health care, it is also necessary to go deeper by exploring how technology frames human lives. Only in this way can we move beyond the trap of technologicalism, which holds not only that science and technology are the main driving forces in our lives, but also that humans should follow these forces and adjust their values and views accordingly. The essays in this issue suggest that humans should instead rely on their full set of values (which are not and should never be determined by technology) to determine and regulate the use of AI in medicine. This mission requires profound philosophical and ethical reflection.