Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Title

Palladium/silver-cocatalyzed tandem reactions of oxabenzonorbornadienes with substituted arylacetylenes: A simple method for the preparation of 1,2-diarylethanones and 1,2-diarylacetylenes

Language

English

Abstract

The effective synthesis of 1,2-diarylethanones was achieved using palladium(II) acetate [Pd(OAc)2] and silver triflate (AgOTf) as cocatalysts from various oxabenzonorbornadiene derivatives and substituted arylacetylenes via tandem reactions under mild conditions. Exploration of the oxabenzonorbornadiene substrates showed that the 1,2-diarylacetylenes were obtained from adjacent alkoxy substituted oxabenzonorbornadiene derivatives. Preliminary mechanistic studies indicate that the AgOTf served as an indispensable catalyst, and the mechanism of the tandem reaction was proposed.

Publication Date

9-30-2015

Source Publication Title

Organometallics

Volume

34

Issue

17

Start Page

4318

End Page

4322

Publisher

American Chemical Society

Peer Reviewed

1

DOI

10.1021/acs.organomet.5b00551

Link to Publisher's Edition

http://dx.doi.org/10.1021/acs.organomet.5b00551

ISSN (print)

02767333

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